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Reports of gene-edited babies spawn investigations

CRISPR mechanism
CRISPR-Cas9 technology uses “molecular scissors” to cut and splice DNA. (UC-Berkeley Graphic)

Multiple investigations are being sought in the wake of reports that a Chinese laboratory facilitated the birth of twin girls whose genes had been edited to protect them against the HIV virus that causes AIDS.

The first-of-its-kind experiment, which took advantage of the CRISPR gene-editing technique, came to light in reports published late Sunday by MIT Technology Review and The Associated Press. The researcher in charge of the project, He Jiankui of the Southern University of Science and Technology in Shenzhen, also published a series of videos explaining the gene-editing project.

There has been no outside confirmation of He’s claims, but geneticists and health policymakers say such claims raise grave ethical issues — including the prospect of creating designer babies, enhancing traits and even introducing exotic new traits.

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By Alan Boyle

Mastermind of Cosmic Log, contributing editor at GeekWire, author of "The Case for Pluto: How a Little Planet Made a Big Difference," president of the Council for the Advancement of Science Writing. Check out "About Alan Boyle" for more fun facts.

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