Tag Archives: Proteins

A-Alpha Bio wins grant to work on molecular glue

A-Alpha Bio, a Seattle venture that began at the University of Washington, has won a $620,472 grant from the National Science Foundation to develop a system that identifies molecules capable of taking disease-causing proteins out of circulation. The Phase II Small Business … Continue reading

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Scientists chart weak spots in coronavirus protein

Chinese researchers say they’ve mapped out a key protein structure in the virus that causes COVID-19, including the likeliest target for the antiviral drug remdesivir. What’s more, they say that same atomic-scale target, known as nsp12, could be attacked by other … Continue reading

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Protein puzzle game finds 99 ways to beat virus

Who would have thought a video game could identify potential treatments for COVID-19? Researchers at the University of Washington’s Institute for Protein Design certainly thought so, and so far the game has produced 99 chances to win. The game is a protein-folding puzzler … Continue reading

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Scientists get a fix on coronavirus’ deadly weapon

Biochemists have created the first 3-D, atomic-scale map of key proteins in the killer coronavirus, opening up new possibilities for developing treatments and a vaccine. Researchers at the University of Washington and its Institute for Protein Design are among the sleuths who’ll … Continue reading

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A-Alpha Bio raises $2.8M for drug discovery

A Seattle startup that took root at the University of Washington has closed a $2.8 million seed round for a drug discovery platform that can sort through millions of protein interactions at once. “We expect that we can go considerably … Continue reading

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Protein designers get a $45 million boost

The era of engineering proteins for medical applications just got a lot closer, thanks to a five-year, $45 million grant from The Audacious Project at TED to the Institute for Protein Design at the University of Washington School of Medicine. The institute, headed by … Continue reading

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Scientists design proteins that snap together

Researchers have created molecular building blocks that can weave themselves into long threads of protein. Well, maybe not all that long. Each protein-based building block measures only a nanometer in length, and the self-assembled filaments get about as long as 10,000 nanometers. … Continue reading

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Scientists pull out protein data from single cells

Scientists have developed a technique that can analyze fluid from a single human cell to identify its proteins — which could open the way for tracking the progression of cancer one cell at a time. The method is known as NanoPOTS, … Continue reading

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Protein designers get a boost for flu vaccine project

The University of Washington’s Institute for Protein Design has won an $11.3 million grant from the Open Philanthropy Project to cook up a public health breakthrough: a universal flu vaccine. This marks the San Francisco-based nonprofit group’s first gift to a research effort in … Continue reading

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Scientists build proteins into molecular capsules

University of Washington researchers have taken a page from the viral playbook to create microscopic assemblies for packaging genetic material — with the goal of using the system for targeted drug delivery. The assemblies, known as synthetic nucleocapsids, work like viruses … Continue reading

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