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Fiction Science Club

How a brainstorm could unlock mysteries of the mind

The Allen Institute’s OpenScope program lets scientists study the weird workings of the brain — for instance, how magic mushrooms work their psychedelic magic on neurons, how memories of the past influence perceptions of the present, and how the brain’s visual system interprets motion and texture.

But one of the program’s leaders, neuroscientist Jerome Lecoq, says he’s really excited about an experiment that hasn’t yet been fully defined. It’s a study that could support a theory about the mechanism by which sensory data is fed into our consciousness — to modify our view of the world, and perhaps to modify our behavior as well.

The experiment is being fine-tuned online by an international community of researchers, through an open-source process that the Seattle-based Allen Institute fittingly calls a “brainstorm.”

“You can just go and follow us on Twitter and visit the Google Doc,” Lecoq says in the latest episode of the Fiction Science podcast. “We’re going to meet in two weeks and a half in Boston at a conference and discuss this experiment. The document is very open. If you have a good idea, please chime in.”

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Fiction Science Club

Scientist takes a trip to the frontiers of consciousness

Could magic mushrooms hold the key that unlocks the secrets of consciousness?

Well, maybe not the only key. But Allen Institute neuroscientist Christof Koch says that hallucinogenic drugs such as psilocybin, the active ingredient found in special types of mushrooms, can contribute to clinical research into the roots of depression, ecstasy and what lies beneath our sense of self.

“What they can teach us about consciousness is that the self is just one aspect of consciousness,” Koch says in the latest episode of the Fiction Science podcast. “You’re still highly conscious, and very often this is associated with states of ecstasy, or states of fear or terror, or a combination of ecstasy and terror. … What’s remarkable is that in all of these states, the self is gone, and very often the external world is gone, yet you’re highly conscious.”

The quest to understand consciousness through detailed analysis of the brain’s structure and function, scientific studies of religious and traditional practices — and yes, research into the effects of psychedelic drugs — is the focus of a 102-minute documentary film titled “Aware: Glimpses of Consciousness.”

“Aware” has been on the film-festival circuit for weeks, and an online showing will be the centerpiece of a live-streaming event set for Nov. 10. The documentary will also air on PBS stations next April as part of public TV’s Independent Lens series.

Koch, who’s the chief scientist of the Seattle-based Allen Institute’s MindScope brain-mapping program, is one of the stars of the show.